DT: Cristian González PeretInter Miami4-3-3| # | Team | MP | GD | Pts |
|---|---|---|---|---|
| 1 |  Nashville SC | 29 | +41 | 66 |
| 2 | Inter Miami | 29 | +20 | 52 |
| 3 |  New England | 29 | +7 | 49 |
| 4 |  Chicago Fire | 29 | +9 | 48 |
| 5 |  Charlotte | 29 | +8 | 46 |
| 6 |  Philadelphia Union | 29 | +13 | 45 |
| 7 |  Orlando City | 29 | -15 | 38 |
| 8 |  New York RB | 29 | -15 | 36 |
| 9 |  Cincinnati | 28 | -8 | 36 |
| 10 |  New York City | 29 | +2 | 33 |
| 11 |  Toronto | 29 | -11 | 33 |
| 12 |  DC United | 28 | -11 | 33 |
| 13 |  Columbus Crew | 29 | -3 | 32 |
| 14 |  Atlanta United | 29 | -12 | 30 |
| 15 |  CF Montréal | 29 | -24 | 24 |
