DT: Ángel Hoyos MarchisioInter Miami4-3-3| # | Team | MP | GD | Pts |
|---|---|---|---|---|
| 1 |  Nashville SC | 27 | +34 | 60 |
| 2 |  New England | 27 | +9 | 46 |
| 3 | Inter Miami | 26 | +15 | 46 |
| 4 |  Charlotte | 27 | +9 | 43 |
| 5 |  Chicago Fire | 26 | +8 | 42 |
| 6 |  Philadelphia Union | 27 | +10 | 39 |
| 7 |  Orlando City | 27 | -16 | 34 |
| 8 |  New York RB | 26 | -14 | 33 |
| 9 |  New York City | 27 | +5 | 33 |
| 10 |  Cincinnati | 26 | -9 | 33 |
| 11 |  DC United | 26 | -8 | 30 |
| 12 |  Toronto | 27 | -12 | 29 |
| 13 |  Atlanta United | 27 | -13 | 27 |
| 14 |  Columbus Crew | 26 | -5 | 26 |
| 15 |  CF Montréal | 27 | -20 | 24 |
