DT: Martín PerelmanOrlando City4-4-2| # | Team | MP | GD | Pts |
|---|---|---|---|---|
| 1 |  Nashville SC | 26 | +32 | 57 |
| 2 |  New England | 26 | +12 | 46 |
| 3 |  Inter Miami | 26 | +15 | 46 |
| 4 |  Charlotte | 26 | +10 | 43 |
| 5 |  Chicago Fire | 25 | +7 | 39 |
| 6 |  Philadelphia Union | 26 | +8 | 36 |
| 7 | Orlando City | 26 | -14 | 34 |
| 8 |  New York RB | 26 | -14 | 33 |
| 9 |  Cincinnati | 25 | -7 | 33 |
| 10 |  New York City | 26 | +5 | 32 |
| 11 |  DC United | 25 | -8 | 29 |
| 12 |  Toronto | 26 | -10 | 29 |
| 13 |  Columbus Crew | 26 | -5 | 26 |
| 14 |  Atlanta United | 26 | -13 | 26 |
| 15 |  CF Montréal | 26 | -22 | 21 |
