| # | Team | MP | GD | Pts |
|---|---|---|---|---|
| 1 |  Nashville SC | 33 | +44 | 74 |
| 2 |  Inter Miami | 33 | +21 | 59 |
| 3 |  New England | 33 | +9 | 58 |
| 4 |  Chicago Fire | 33 | +11 | 55 |
| 5 |  Charlotte | 33 | +15 | 53 |
| 6 |  Philadelphia Union | 33 | +11 | 47 |
| 7 |  Cincinnati | 33 | -6 | 46 |
| 8 |  Columbus Crew | 33 | +6 | 44 |
| 9 |  Orlando City | 33 | -16 | 43 |
| 10 |  New York RB | 33 | -17 | 39 |
| 11 |  New York City | 33 | +3 | 39 |
| 12 |  Toronto | 33 | -12 | 39 |
| 13 |  Atlanta United | 33 | -14 | 33 |
| 14 |  DC United | 33 | -21 | 33 |
| 15 |  CF Montréal | 33 | -30 | 26 |